What is it? How does it work? Evidence Indications
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PROMOGRAN®

 


PROMOGRAN® is sterile, freeze-dried composite of 55% collagen and 45% oxidised regenerated cellulose (ORC).
PROMOGRAN® is designed to promote an optimal healing environment 1


With PROMOGRAN® stalled wounds close:
• Faster 1,2
• Cost Effectively 1,3,4

In the presence of exudate the PROMOGRAN® protease modulating matrix transforms into a soft and conformable, biodegradable gel: this allows contact with all areas of the wound.


Click this link to view PROMOGRAN® product codes


Disclaimer

The product information on this page is not intended to be used by health care professinoals or users in the United States and may not comply with the regulatory standards of the United States – please click the link above for product information in respect of products used in the United States

 

© Systagenix Wound Management 2011. Brands marked with ® or ™ are trademarks of Systagenix. All other products referenced herein are acknowledged to be trademarks of their respective owners.

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The product information on this page is not intended to be used by health care professinoals or users in the United States and may not comply with the regulatory standards of the United States – please click the link above for product information in respect of products used in the United States

How PROMOGRAN® Works

Collagen/ORC has been proven to reduce levels of Proteases such as MMPs and Elastase.
This may restore the balance of the wound microenvironment, promoting granulation tissue and helping the wound close.5

cOLL orc GRAPH

 

By reducing both MMP and Elastase activity the wound surface area has been shown to reduce. Collagen alone has been shown to be less effective at reducing protease activity.

 

PROTEASE GRAPHS

 

Click here for further information on the role of Proteases in wound healing.

Disclaimer

The product information on this page is not intended to be used by health care professinoals or users in the United States and may not comply with the regulatory standards of the United States – please click the link above for product information in respect of products used in the United States

heal_icon

Disclaimer

The product information on this page is not intended to be used by health care professinoals or users in the United States and may not comply with the regulatory standards of the United States – please click the link above for product information in respect of products used in the United States

PROMOGRAN® Evidence

Please click on the table below for the full list of PROMOGRAN® evidence:

For more detailed clinical and in vitro work on the benefits of PROMOGRAN®, please click one of the links below.


• OWM Health Economic Supplement, November 2010
• Wounds International MMPs Made Easy
• Wounds International PROMOGRAN® & PROMOGRAN PRISMA® Made Easy
• Cullen at al EWMA 2010 ORC
• Cullen et al EWMA 2010 evidence
• Cullen et al (2009) SAWC Poster (In-vitro, Clinical)
• SAWC 2009 Bacteria BC.
• SAWC poster Promogran+awd cell CWF
• Silcock (2009) SAWC Poster (Review)
• Reed Promogran plus VAC (Case Study)
• DFU poster WUWHS July 04.pdf
• Evidence Poster Harrogate 2010. CollagenORC

 

 

Click here for further information on the role of Proteases in wound healing.

Systagenix is not responsible for the content of external websites.

Disclaimer

The product information on this page is not intended to be used by health care professinoals or users in the United States and may not comply with the regulatory standards of the United States – please click the link above for product information in respect of products used in the United States

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PROMOGRAN® Indications

PROMOGRAN® matrix is indicated for the management of all wounds
healing by secondary intent which are clear of necrotic tissue, including:

  • Diabetic ulcers
  • Venous ulcers
  • Pressure ulcers
  • Ulcers caused by mixed vascular aetiologies
  • Traumatic and surgical wounds

PROMOGRAN® matrix has demonstrated haemostatic properties.
PROMOGRAN® matrix can be used under compression therapy.

Please refer in full to the Instructions for use leaflet provided in the product packaging.

Click here for references
 
 
 
Let's Heal™ is the unique system developed by Systagenix which represents the world's first integrated wound healing system,
allowing the clinician to "test and treat" wounds at the point of care.
With a wealth of clinical and scientific evidence that is hard to match, and a team of professionals continuing to raise the standards of innovation and expertise, we are committed to developing wound care solutions to help wounds heal, fast.
Meet the Systagenix Leadership Team, Clinical Advisory Board, and Board of Directors
Systagenix sales and marketing teams provide support in over 100 countries worldwide. For dedicated wound healing education and services, contact Systagenix directly to make an appointment now.
 
 

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Now Playing: WOUNDCHEK™ Protease Status Specimen Collection (Serena's Technique)

Description:
1. Prior to swabbing, cleanse the wound with sterile saline to remove all loose debris, remains of therapeutic agents and necrotic tissue.
2. Ensure that complete hemostasis has been achieved before obtaining the specimen. Do not perform sharp wound debridement prior to sample collection.
3. Moisten wound area to be swabbed with a few (up to five) drops of saline. Care should be taken not to flood the wound with excessive saline.
4. Avoid swabbing areas that contain blood, necrotic material, thick slough or fibrinous tissue.
5. Using a sterile swab provided in the kit, collect the wound fluid sample by pressing the head of the swab flat against the base of the wound and gently rolling it back and forth several times while applying pressure. Continue rolling the swab head until fully coated and discoloured by wound fluid.
6. Test fresh sample swabs as soon as possible after collection. Follow test procedure instructions.

Disclaimer
The product information on this page is not intended for, or to be used by health care professionals or users in the United States

Video footage kindly provided by SerenaGroup

SerenaGroup, 311 Pennsylvania Ave. West, Warren, PA 16365, USA, For more information email: Systagenix.

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WOUNDCHEK™ Protease Status Specimen Collection (Serena's Technique)

Description:
1. Prior to swabbing, cleanse the wound with sterile saline to remove all loose debris, remains of therapeutic agents and necrotic tissue.
2. Ensure that complete hemostasis has been achieved before obtaining the specimen. Do not perform sharp wound debridement prior to sample collection.
3. Moisten wound area to be swabbed with a few (up to five) drops of saline. Care should be taken not to flood the wound with excessive saline.
4. Avoid swabbing areas that contain blood, necrotic material, thick slough or fibrinous tissue.
5. Using a sterile swab provided in the kit, collect the wound fluid sample by pressing the head of the swab flat against the base of the wound and gently rolling it back and forth several times while applying pressure. Continue rolling the swab head until fully coated and discoloured by wound fluid.
6. Test fresh sample swabs as soon as possible after collection. Follow test procedure instructions.

Disclaimer
The product information on this page is not intended for, or to be used by health care professionals or users in the United States